By : Lamiaa Moustafa Elbosaty
Dementia due to Pick's Disease: The onset of Pick's disease is between 40 and 60 years of age; it occurs slightly more in men, usually those with first degree relative with the illness. Although the cause is unknown, genetic factors are suspected (Sadock & Sadock, 2003). Pick's disease is another degenerative cognitive disorder that resembles Alzheimer's disease in its clinical picture that in several instances it is only at autopsy that differentiation can take place. General microscopic findings include atrophy of the front temporal regions of the brain, in contrast to the more parietal-temporal distribution in Alzheimer's disease (Arciniegas & Dubovsky, 2001). The victims of this disorder have less disorientation and memory loss than those with Alzheimer's disease and more personality changes, including loss of social constraints (resulting in frequent behavioral problems) (Mohr, 2006).
- Dementia due to Vitamin B12 Deficiency: The prevalence of vitamin B12 deficiency in patients with dementia varies significantly, but the incidence of reversible vitamin B12 deficiency as the primary etiology is probably less than one percent. Cognitive deficits may include poor spatial coping skills, diminished episodic memory, and impaired abstract thinking (Whyte et al., 2002).
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